郑州天顺食品添加剂有限公司

郑州食品添加剂网|河南食品添加剂生产厂家常年供应食品级食品添加剂!

全国服务热线 15003810456
您所在的位置:

欧盟评估大肠杆菌DSM 32731生产的玉米赤霉烯酮水解酶作为所有陆生动物饲料添加剂的安全性和有效性

来源:郑州天顺食品添加剂有限公司 发布时间:2022-02-25 16:50:23 关注: 0 次
标签: , , , , ,

   食用添加剂网讯  2022年2月24日,据欧盟国家食品安全局(EFSA)信息,应欧洲委员会规定,欧盟国家小动物饲料添加物和商品(FEEDAP)科学研究工作组就大肠埃希菌DSM 32731生产制造的苞米赤霉烯酮核糖核苷酸(zearalenone hydrolase)做为全部陆生动物饲料添加物的安全系数和实效性发布科学合理建议。

  通过评定,权威专家工作组没法就添加物对总体目标外来物种、顾客、使用人和条件的安全系数作出结果。一部分全文报导如下所示:
  Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on zearalenone hydrolase (ZenA) produced by Escherichia coli DSM 32731 when used as a feed additive for all terrestrial animals. The production strain E. coli DSM 32731 is genetically modified and harbours a kanamycin resistance gene. No viable cells of the production strain were detected in the final product, but uncertainty remains on the presence of recombinant DNA in the final product. The ZenA contained in the additive is safe for all terrestrial animal species up to the maximum use levels of (in U/kg complete feed): 100 U/kg in chickens for fattening; 150 U/kg in laying hens, turkeys for fattening and rabbits; 200 U/kg in pigs; 250 U/kg in dairy cows; 400?U/kg in veal calf (milk replacer), cattle for fattening, sheep, goats, horses and cats; and 450 U/kg in dogs. based on the ADME and toxicological data, the FEEDAP Panel considers that the use of the ZenA contained in the additive in animal nutrition is safe for the consumers. The endotoxin content in the additive poses a risk by inhalation for users handling the additive. The additive is not a skin/eye irritant nor a skin sensitiser. Due to its proteinaceous nature, the additive should be considered as a potential respiratory sensitiser. The ZenA contained in the additive and the resulting breakdown products of its enzymatic activity do not represent a safety concern for the environment. The production strain harbours an antimicrobial resistance gene and uncertainties remain on the possible presence of its recombinant DNA in the final product; therefore, the FEEDAP Panel cannot conclude on safety of the additive for the target species, the consumer, the user and the environment.

文章版权备注

文章版权归 郑州天顺食品添加剂有限公司 所有
文章链接:https://www.tsswhg.com/24615.html
未经授权,禁止任何站点镜像、采集、或复制本站内容,违者通过法律途径维权到底!